Mercedes-Benz E-class W212/S212/C207/A207 facelift (2013-2016) blu/blk Wiring diagrams

1 2 3 4 5 6 7 8 9 CAN-B H CAN-B L 10 11 12 13 14 15 16 LIN DATA 3.5L AIR RECIRCULATION MODE BUTTON AUTOMATIC AIR CONDITIONING CONTROL, OPERATING UNIT BLU/BLK WIRE BLU/GRN WIRE BLU/GRY WIRE BLU/PNK WIRE BLU/VIO WIRE BRN WIRE BRN/BLK WIRE BRN/BLU WIRE BRN/GRN WIRE BRN/GRY WIRE BRN/PNK WIRE BRN/RED WIRE BRN/VIO WIRE COMPUTER DATA LINES SYSTEM COUPE EVAPORATOR TEMPERATURE SENSOR (LOWER RIGHT SIDE OF HVAC EVAPORATOR ASSEMBLY) FRONT SAM CONTROL MODULE W/ FUSE, RELAY MODULE (LEFT REAR OF ENGINE COMPT) FUSE 12 GND (-) 31 GRN WIRE GRY/BLU WIRE HOT AT ALL TIMES INTERIOR HUMIDITY/ TEMPERATURE SENSOR (IF EQUIPPED) (TOP CENTER OF WINDSHIELD) INTERIOR TEMPERATURE SENSOR (LEFT CENTER OF DASH) INTERIOR TEMPERATURE SENSOR W/ INTEGRATED FAN LEFT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT FRONT SIDE AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT SIDE AIR OUTLET TEMPERATURE SENSOR (LEFT SIDE OF DASH) NCA WIRE OVERHEAD CONTROL PANEL ELECTRONICS (W/O CAN) REAR WINDOW HEATER BUTTON RED/BLK WIRE RED/BRN WIRE RED/VIO WIRE REFRIGERANT COMPRESSOR (LOWER LEFT FRONT ENGINE) REFRIGERANT PRESSURE SENSOR (LOWER LEFT SIDE OF RADIATOR ON REFRIGERANT LINE) RIGHT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) RIGHT FRONT FOOTWELL AIR OUTLET TEMPERATURE SENSOR (RIGHT FRONT FOOTWELL AREA) RIGHT FRONT SIDE AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) RIGHT SIDE AIR OUTLET TEMPERATURE SENSOR (RIGHT SIDE OF DASH) SIG SIG SOLID STATE SUN SENSOR (TOP CENTER OF DASH) VIO/WHT WIRE WHT/BLU WIRE YEL/BLU WIRE

1 2 3 4 5 6 7 8 9 COMPUTER DATA LINES SYSTEM CAN B H CAN B L 1 2 GND DATA 10 11 12 13 14 15 16 LIN DATA 3.5L, 4.6L TURBO 30 GND 31 AIR RECIRCULATION MODE BUTTON AUTOMATIC AIR CONDITIONING CONTROL, OPERATING UNIT BLU GRY/ WIRE BLU/BLK WIRE BLU/GRN WIRE BLU/GRY WIRE BLU/PNK WIRE BLU/VIO WIRE BRN WIRE BRN/BLK WIRE BRN/BLU WIRE BRN/GRN WIRE BRN/GRY WIRE BRN/PNK WIRE BRN/RED WIRE BRN/VIO WIRE COUPE EMISSIONS SENSOR (RIGHT REAR OF ENGINE COMPT) EVAPORATOR TEMPERATURE SENSOR (LOWER RIGHT SIDE OF HVAC EVAPORATOR ASSEMBLY) FRONT SAM CONTROL MODULE W/ FUSE, RELAY MODULE (LEFT REAR OF ENGINE COMPT) FUSE 12 GRN WIRE GRY/BLU WIRE HOT AT ALL TIMES INTERIOR HUMIDITY/ TEMPERATURE SENSOR (IF EQUIPPED) (TOP CENTER OF WINDSHIELD) INTERIOR TEMPERATURE SENSOR (LEFT CENTER OF DASH) INTERIOR TEMPERATURE SENSOR W/ INTEGRATED FAN LEFT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT FRONT FOOTWELL AIR OUTLET TEMPERATURE SENSOR (LEFT FRONT FOOTWELL AREA) LEFT FRONT SIDE AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT SIDE AIR OUTLET TEMPERATURE SENSOR (LEFT SIDE OF DASH) NCA WIRE OVERHEAD CONTROL PANEL ELECTRONICS (W/O CAN) REAR AUTOMATIC AIR CONDITIONING OPERATING UNIT REAR FOOTWELL AIR OUTLET REAR WINDOW HEATER BUTTON RED/BLK WIRE RED/BRN WIRE RED/VIO WIRE RED/WHT WIRE REFRIGERANT COMPRESSOR (LOWER LEFT FRONT ENGINE) REFRIGERANT PRESSURE SENSOR (LOWER LEFT SIDE OF RADIATOR ON REFRIGERANT LINE) RIGHT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) RIGHT FRONT FOOTWELL AIR OUTLET TEMPERATURE SENSOR (RIGHT FRONT FOOTWELL AREA) RIGHT SIDE AIR OUTLET TEMPERATURE SENSOR (RIGHT SIDE OF DASH) SIG SIG SIG SIG DATA FOND GND SOLID STATE SUN SENSOR (TOP CENTER OF DASH) TEMPERATURE SENSOR (REAR OF CENTER CONSOLE) VIO/WHT WIRE W/ AIR OUTLET SYMBOL ILLUMINATION WHT/BLU WIRE YEL/BLU WIRE

1 2 3 4 5 6 7 8 9 CAN-B H CAN-B L 10 11 12 13 14 15 16 LIN DATA 3.5L AIR RECIRCULATION MODE BUTTON AUTOMATIC AIR CONDITIONING CONTROL, OPERATING UNIT BLU/BLK WIRE BLU/GRN WIRE BLU/GRY WIRE BLU/PNK WIRE BLU/VIO WIRE BRN WIRE BRN/BLK WIRE BRN/BLU WIRE BRN/GRN WIRE BRN/GRY WIRE BRN/PNK WIRE BRN/RED WIRE BRN/VIO WIRE COMPUTER DATA LINES SYSTEM COUPE EVAPORATOR TEMPERATURE SENSOR (LOWER RIGHT SIDE OF HVAC EVAPORATOR ASSEMBLY) FRONT SAM CONTROL MODULE W/ FUSE, RELAY MODULE (LEFT REAR OF ENGINE COMPT) FUSE 12 GND (-) 31 GRN WIRE GRY/BLU WIRE HOT AT ALL TIMES INTERIOR HUMIDITY/ TEMPERATURE SENSOR (IF EQUIPPED) (TOP CENTER OF WINDSHIELD) INTERIOR TEMPERATURE SENSOR (LEFT CENTER OF DASH) INTERIOR TEMPERATURE SENSOR W/ INTEGRATED FAN LEFT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT FRONT SIDE AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT SIDE AIR OUTLET TEMPERATURE SENSOR (LEFT SIDE OF DASH) NCA WIRE OVERHEAD CONTROL PANEL ELECTRONICS (W/O CAN) REAR WINDOW HEATER BUTTON RED/BLK WIRE RED/BRN WIRE RED/VIO WIRE REFRIGERANT COMPRESSOR (LOWER LEFT FRONT ENGINE) REFRIGERANT PRESSURE SENSOR (LOWER LEFT SIDE OF RADIATOR ON REFRIGERANT LINE) RIGHT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) RIGHT FRONT FOOTWELL AIR OUTLET TEMPERATURE SENSOR (RIGHT FRONT FOOTWELL AREA) RIGHT FRONT SIDE AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) RIGHT SIDE AIR OUTLET TEMPERATURE SENSOR (RIGHT SIDE OF DASH) SIG SIG SOLID STATE SUN SENSOR (TOP CENTER OF DASH) VIO/WHT WIRE WHT/BLU WIRE YEL/BLU WIRE

1 2 3 4 5 6 7 8 9 COMPUTER DATA LINES SYSTEM CAN B H CAN B L 1 2 GND DATA 10 11 12 13 14 15 16 LIN DATA 3.5L, 4.6L TURBO 30 GND 31 AIR RECIRCULATION MODE BUTTON AUTOMATIC AIR CONDITIONING CONTROL, OPERATING UNIT BLU GRY/ WIRE BLU/BLK WIRE BLU/GRN WIRE BLU/GRY WIRE BLU/PNK WIRE BLU/VIO WIRE BRN WIRE BRN/BLK WIRE BRN/BLU WIRE BRN/GRN WIRE BRN/GRY WIRE BRN/PNK WIRE BRN/RED WIRE BRN/VIO WIRE COUPE EMISSIONS SENSOR (RIGHT REAR OF ENGINE COMPT) EVAPORATOR TEMPERATURE SENSOR (LOWER RIGHT SIDE OF HVAC EVAPORATOR ASSEMBLY) FRONT SAM CONTROL MODULE W/ FUSE, RELAY MODULE (LEFT REAR OF ENGINE COMPT) FUSE 12 GRN WIRE GRY/BLU WIRE HOT AT ALL TIMES INTERIOR HUMIDITY/ TEMPERATURE SENSOR (IF EQUIPPED) (TOP CENTER OF WINDSHIELD) INTERIOR TEMPERATURE SENSOR (LEFT CENTER OF DASH) INTERIOR TEMPERATURE SENSOR W/ INTEGRATED FAN LEFT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT FRONT FOOTWELL AIR OUTLET TEMPERATURE SENSOR (LEFT FRONT FOOTWELL AREA) LEFT FRONT SIDE AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) LEFT SIDE AIR OUTLET TEMPERATURE SENSOR (LEFT SIDE OF DASH) NCA WIRE OVERHEAD CONTROL PANEL ELECTRONICS (W/O CAN) REAR AUTOMATIC AIR CONDITIONING OPERATING UNIT REAR FOOTWELL AIR OUTLET REAR WINDOW HEATER BUTTON RED/BLK WIRE RED/BRN WIRE RED/VIO WIRE RED/WHT WIRE REFRIGERANT COMPRESSOR (LOWER LEFT FRONT ENGINE) REFRIGERANT PRESSURE SENSOR (LOWER LEFT SIDE OF RADIATOR ON REFRIGERANT LINE) RIGHT CENTER AIR OUTLET SYMBOL ILLUMINATION (IF EQUIPPED) RIGHT FRONT FOOTWELL AIR OUTLET TEMPERATURE SENSOR (RIGHT FRONT FOOTWELL AREA) RIGHT SIDE AIR OUTLET TEMPERATURE SENSOR (RIGHT SIDE OF DASH) SIG SIG SIG SIG DATA FOND GND SOLID STATE SUN SENSOR (TOP CENTER OF DASH) TEMPERATURE SENSOR (REAR OF CENTER CONSOLE) VIO/WHT WIRE W/ AIR OUTLET SYMBOL ILLUMINATION WHT/BLU WIRE YEL/BLU WIRE

21 23 24 13 12 BLS H BLS M 31 30 CAN B L CAN B H 4 2 WAGON SEDAN 4 7 10 RFL L NSL R SL/BL 5 25 26 DIAG 5 9 6 RFL L SL/BL NSL L 6 15 27 DIAG ACOUSTIC TURN SIGNAL LIGHT FUNCTION CHECK BACK- GROUND, TAIL LIGHT BACKUP LAMP BLK WIRE BLK/BLU WIRE BLK/GRN WIRE BLK/RED WIRE BLK/WHT WIRE BLU WIRE BLU/BLK WIRE BLU/GRN WIRE BLU/GRY WIRE BLU/WHT WIRE BRAKE LIGHT TAIL LIGHT/ BRN WIRE BRN/RED WIRE COMPUTER DATA LINES SYSTEM GRN WIRE GRN/BRN WIRE GRN/WHT WIRE GRY WIRE GRY/BLK WIRE GRY/BLU WIRE GRY/RED WIRE GRY/VIO WIRE INNER LEFT REAR LAMP UNIT INSIDE TAIL LIGHT (SEDAN) FOG LAMP (WAGON) INSIDE TAIL LIGHT (WAGON) FOG LAMP (SEDAN) INSTRUMENT CLUSTER LEFT "C" PILLAR) LEFT REAR LAMP UNIT LEFT TURN SIGNAL IND LIGHT PNK 2 4 WIRE REAR FOG LAMP IND REAR SAM CONTROL UNIT W/ FUSE, RELAY MODULE (RIGHT SIDE OF LUGGAGE COMPT) RED WIRE RED/BLK WIRE REGENERATIVE BRAKING SYSTEM CONTROL UNIT (HYBRID) RIGHT TURN SIGNAL IND LIGHT SEDAN SIDE MARKER LAMP BACKGROUND LIGHT SML BSL L SMR BSL R TURN SIGNAL LAMP VIO/BLU WIRE WAGON WHT WIRE YEL WIRE YEL/PNK WIRE YEL/VIO WIRE YEL/WHT WIRE

10 32 6 30 BLS V BLS M BLS L BLS H 21 23 24 13 12 BLS H BLS M 31 30 COMPUTER DATA LINES SYSTEM CAN B L CAN B H 4 2 WAGON SEDAN (NOT USED) 4 7 10 RFL L NSL R SL/BL 5 25 26 DIAG 5 9 6 15 12 RFL L SL/BL NSL L 6 15 27 DIAG ANALOG CLOCK BLK WIRE BLK/BLU WIRE BLK/GRN WIRE BLK/RED WIRE BLK/WHT WIRE BLU WIRE BLU/BLK WIRE BLU/GRN WIRE BLU/GRY WIRE BLU/WHT WIRE BRN WIRE BRN/RED WIRE COMPUTER DATA LINES SYSTEM GRN WIRE GRN/BRN WIRE GRN/WHT WIRE GRY WIRE GRY/BLK WIRE GRY/BLU WIRE GRY/RED WIRE GRY/VIO WIRE INNER LEFT REAR LAMP UNIT INSIDE TAIL LIGHT (SEDAN) FOG BACKUP LAMP LAMP (WAGON) INSIDE TAIL LIGHT (WAGON) BACK- FOG GROUND LAMP, TAIL (SEDAN) LIGHT LIN 1 ORG/ WIRE PNK 2 4 3 3 WIRE PREMIUM ELECTRONIC STABILITY PROGRAM CONTROL UNIT (EXCEPT HYBRID) REAR SAM CONTROL UNIT W/ FUSE, RELAY MODULE (RIGHT SIDE OF LUGGAGE COMPT) RED WIRE RED/BLK WIRE RED/WHT WIRE RED/YEL WIRE REGENERATIVE BRAKING SYSTEM CONTROL UNIT (HYBRID) RIGHT FRONT LAMP RIGHT FRONT SIDE MARKER LAMP RIGHT FRONT TURN SIGNAL LAMP RIGHT HEADLAMP CONTROL UNIT RIGHT LED SIGNALING LIGHTS ACTUATION MODULE FAN MOTOR RIGHT PARKING LIGHT, DAYTIME RUNNING LIGHT SEDAN SEDAN WAGON SML BSL L SMR BSL R UNIT) UPPER CONTROL PANEL CONTROL UNIT HAZARD WARNING SYSTEM BUTTON VIO/BLU WIRE WAGON WHT WIRE YEL WIRE YEL/PNK WIRE YEL/VIO WIRE YEL/WHT WIRE

1 2 3 31 30 LIN 2 1 2 3 4 5 6 30 SIG SIG SIG SIG 31 1 2 3 4 5 6 7 8 9 10 (-) (+) (+) (-) FL 1 2 3 4 5 6 7 8 LIN 2 LL L LL R 1 2 3 4 5 6 IRS OFF IRS LED 31 ASS LED ASS OFF AMBIENT LAMP BLK WIRE BLK/GRY WIRE BLU WIRE BLU/BLK WIRE BLU/GRY WIRE BLU/WHT WIRE BRN WIRE BRN/BLK WIRE BRN/GRY WIRE BRN/YEL WIRE FORWARD AUTOMATIC AUTOMATIC DIMMING DIMMING MIRROR MIRROR LIGHT SENSOR FRONT DOME LAMP SWITCH FRONT ELECTRICAL PREFUSE BOX FRONT SAM CONTROL MODULE W/ FUSE/RELAY MODULE (LEFT REAR OF ENGINE COMPT) FUSE 157 154 GARAGE DOOR OPENER GARAGE DOOR OPENER BUTTON 1 GARAGE DOOR OPENER BUTTON 2 GARAGE DOOR OPENER BUTTON 3 GARAGE DOOR OPENER INDICATOR LAMP GRN PNK/ WIRE GRN WIRE GRY WIRE GRY/BLU WIRE GRY/YEL WIRE HANDS-FREE SYSTEM HOT AT ALL TIMES INSIDE REARVIEW MIRROR INTERIOR LAMP AUTOMATIC FUNCTION SWITCH INTERIOR PROTECTION SWITCH (W/ TOW-AWAY PROTECTION, INTERIOR PROTECTION) INTERIOR TEMPERATURE SENSOR W/ INTEGRATED FAN LEFT FRONT READING LAMP SWITCH LEFT RIGHT READING READING LAMP LAMP MICROPHONE NAVIGATION SYSTEM NCA WIRE NTC (+) NTC (-) NTC- ORG/ WIRE OVERHEAD CONTROL PANEL ELECTRONICS PANORAMIC SLIDING ROOF SWITCH (IF EQUIPPED) PNK 10 11 12 13 WIRE PNK WIRE PNK/GRN WIRE POWER TOPS SYSTEM REAR DOME LAMP, SWITCH REARWARD AUTOMATIC DIMMING MIRROR LIGHT SENSOR RED WIRE RED/BLK WIRE RED/BLU WIRE RED/GRY WIRE RED/WHT WIRE RED/YEL WIRE RIGHT FRONT READING LAMP SWITCH RIGHT LEFT FRONT FRONT INTERIOR INTERIOR LAMP LAMP SIG IL LIN 2 SOS TOWING SENSOR BUTTON (W/ TOW-AWAY PROTECTION, INTERIOR PROTECTION) USED) VIO WIRE VIO/BLU WIRE VIO/WHT WIRE W/O ECO START/STOP FUNCTION W/ ECO START/STOP FUNCTION YEL WIRE YEL/VIO WIRE

1 2 3 31 30 LIN 2 1 2 3 4 5 6 7 8 (-) (+) (+) (-) FL 1 2 3 4 5 6 7 8 LIN 2 LL L LL R 1 2 3 4 5 6 IRS OFF IRS LED 31 ASS LED ASS OFF 31 HS 1 HS(+) HS 2 MOTOR - MOTOR + AUTOMATIC DIMMING MIRROR BLK WIRE BLK/GRY WIRE BLU WIRE BLU/BLK WIRE BLU/GRY WIRE BRN WIRE BRN/GRY WIRE BRN/RED WIRE BRN/YEL WIRE CAN B L CAN B H LIN 2 COMPUTER DATA LINES SYSTEM FORWARD AUTOMATIC DIMMING MIRROR LIGHT SENSOR FRONT DOME LAMP SWITCH FRONT SAM CONTROL MODULE W/ FUSE/RELAY MODULE (LEFT REAR OF ENGINE COMPT) FUSE 17 GARAGE DOOR OPENER GARAGE DOOR OPENER BUTTON 1 GARAGE DOOR OPENER BUTTON 2 GARAGE DOOR OPENER BUTTON 3 GARAGE DOOR OPENER INDICATOR LAMP GRN WIRE GRY WIRE GRY/BLU WIRE GRY/YEL WIRE HANDS-FREE SYSTEM MICROPHONE HOT W/ QUIESCENT CURRENT CUTOUT RELAY ENERGIZED INSIDE REARVIEW MIRROR INTERIOR LAMP AUTOMATIC FUNCTION SWITCH INTERIOR PROTECTION SWITCH (W/ TOW-AWAY PROTECTION, INTERIOR PROTECTION) INTERIOR TEMPERATURE SENSOR W/ INTEGRATED FAN LEFT FRONT READING LAMP SWITCH LEFT RIGHT AMBIENT READING READING LAMP LAMP LAMP LIN 2 NAVIGATION SYSTEM NCA WIRE ORG/ WIRE OVERHEAD CONTROL PANEL CONTROL UNIT PNK 10 11 12 13 WIRE PNK WIRE PNK/GRN WIRE POWER TOPS SYSTEM REAR DOME LAMP, SWITCH REARWARD AUTOMATIC DIMMING MIRROR LIGHT SENSOR RED WIRE RED/BLK WIRE RED/BLU WIRE RED/GRY WIRE RED/WHT WIRE RED/YEL WIRE RIGHT FRONT READING LAMP SWITCH RIGHT LEFT FRONT FRONT INTERIOR INTERIOR LAMP LAMP SOS TILTING/SLIDING ROOF SWITCH (IF EQUIPPED) TOWING SENSOR BUTTON (W/ TOW-AWAY PROTECTION, INTERIOR PROTECTION) USED) VIO WIRE WHT WIRE YEL WIRE YEL/VIO WIRE

1 2 MOST MOST OUT MOST IN 31 (+) (+) (+) (+) (+) (+) (+) (+) PNK WIRE BLK RED/ WIRE BLK WIRE BLU WIRE BLU/BLK WIRE BLU/WHT WIRE BRN WIRE BRN/BLK WIRE BRN/BLU WIRE BRN/GRN WIRE BRN/GRY WIRE BRN/ORG WIRE BRN/PNK WIRE BRN/VIO WIRE BRN/WHT WIRE BRN/YEL WIRE CENTER INSTRUMENT PANEL SPEAKER FUSE GRN WIRE GRY RED/ WIRE GRY WIRE HOT W/ QUIESCENT CURRENT CUTOUT RELAY ENERGIZED IN 5+ IN 4+ IN 3+ IN 2+ IN 1+ TX IN 5- IN 4- IN 3- IN 2- IN 1- LCT LEFT FRONT DOOR SPEAKER LEFT REAR DOOR SOUND SYSTEM TWEETER LEFT REAR SURROUND SPEAKER MOST DATA BUS CIRCUIT MUTE NCA WIRE ON WAKE UP ORG/ WIRE PNK WIRE RED WIRE RED/BLK WIRE RED/GRY WIRE RIGHT FRONT DOOR SPEAKER RIGHT REAR DOOR SOUND SYSTEM TWEETER RIGHT REAR SURROUND SPEAKER SOUND SYSTEM AMPLIFIER CONTROL UNIT (LEFT SIDE OF LUGGAGE COMPT) SOUND SYSTEM MICROPHONE VIO WIRE WAGON WHT WIRE YEL WIRE

1 2 MOST MOST OUT MOST IN BASS SPEAKER BLK WIRE BLU WIRE BLU/BLK WIRE BLU/BRN WIRE BLU/VIO WIRE BLU/WHT WIRE BRN WIRE BRN/BLU WIRE BRN/GRN WIRE BRN/GRY WIRE BRN/ORG WIRE BRN/PNK WIRE BRN/RED WIRE BRN/VIO WIRE BRN/WHT WIRE BRN/YEL WIRE CENTER INSTRUMENT PANEL SPEAKER FUSE GRN WIRE GRY WIRE HOT W/ QUIESCENT CURRENT CUTOUT RELAY ENERGIZED IN (-) LCT LEFT REAR SURROUND SPEAKER MOST DATA BUS CIRCUIT NCA WIRE ORG/ WIRE PNK WIRE REAR BASS SPEAKER AMPLIFIER (UNDER LEFT CENTER OF HAT SHELF) RED WIRE RED/BLK WIRE RED/GRY WIRE RIGHT REAR SURROUND SPEAKER SEDAN SHIELD SIG SIG MUTE SOUND SYSTEM AMPLIFIER CONTROL UNIT (LEFT SIDE OF LUGGAGE COMPT) TRACER WIRE CONNECTOR SLEEVE VIO WIRE WAGON WAKE UP SIG WHT WIRE YEL WIRE